| 原发性肺癌血清骨钙素水平与骨转移的关系 |
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| 引用本文： | 郑小河,林菁,林楚卿,曾润铭,吴洁文. 原发性肺癌血清骨钙素水平与骨转移的关系[J]. 河北医学, 2010, 16(9): 1039-1041. DOI: 10.3969/j.issn.1006-6233.2010.09.006 |
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| 作者姓名： | 郑小河 林菁 林楚卿 曾润铭 吴洁文 |
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| 作者单位： | 汕头大学医学院第一附属医院呼吸内科,广东,汕头,515041;广东省汕头市第四人民医院,广东,汕头,515041 |
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| 基金项目： | 汕头市重点科技计划项目 |
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| 摘 要： | 目的：观察血清骨钙素水平与肺癌骨转移的关系。方法：应用Pharmacia CAP系统检测86例原发性肺癌和36例正常人血清骨钙素水平。结果：肺癌及其不同细胞类型病人之间以及与正常人比较,无骨转移者血清骨钙素水平无明显差异,伴有骨转移者血清骨钙素水平（6.26±1.68）明显高于无骨转移者（4.53±1.50）和正常人（4.56±1.53）（P〈0.05）。结论：血清骨钙素检测对预示肺癌发生骨转移有参考价值。
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| 关 键 词： | 肺癌 骨钙素 骨转移 |
The Study of Correlation Between Serum Osteocalcin and Bone Metastases in Patients with Lung Cancer |
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| Affiliation: | ZHENG Xiaohe,LIN Jing,et al (The First Affiliated Hospital of Shantou University Medical College,Guangdong Shantou 515041,China) |
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| Abstract: | Objective： To observe the correlation between serum level of osteocalcin and osseous metastasis caused by lung cancer.Method：The Pharmacia CAP system was employed to test the serum osteocalcin in 86 lung cancer patients and 36 healthy controls.Result：The difference of serum osteocalcin between healthy controls and patients without bone metastasis was not obviousp0.05.But the serum osteocalcin in patients with bone metastasis（6.26±1.68） were higher than those without bone metastasis（4.53±1.50） and（4.56±1.53）（P0.05）.Conclusion：The serum osteocalcin could be a good indication to diagnose osseous metastasis caused by lung cancer. |
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| Keywords: | Lung cancer Osteocalcin Osseous metastasis |
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