七叶洋地黄双苷联合托吡卡胺滴眼液对儿童低度近视治疗的临床观察

目的观察七叶洋地黄双苷（施图伦）联合托吡卡胺滴眼液对儿童低度近视治疗的临床效果．方法挑选2010年7月至2013年4月在在昆明医科大学第一附属医院眼科门诊就诊的低度近视患儿（6—14岁）共80人（160眼），根据用药情况的不同分为对照组、施图伦组、托吡卡胺组、施图伦联合托毗卡胺组．共4组，每组20人（40眼）。分别比较各组用药前及用药后2周近视患儿的裸眼视力及矫正度数的改变情况；并对治疗后各组间治疗效果进行比较．结果（1）治疗后对照组、托毗卡胺组、施图伦组较治疗前病情差异无统计学意义（P〉0．05）；（2）治疗后施图伦联合托吡卡胺组较治疗前裸眼视力有提高，差异有统计学意义（P〈0．05）；（3）各组之间治疗前比较差异无统计学意义（P〉0．05）；（4）治疗后施图伦联合托吡卡胺组较其他3组差异有统计学意义（P〈0．05），而其余各组问比较差异无统计学意义（P〉0．05）．结论七叶洋地黄双苷联合托吡卡胺滴眼液对儿童低度近视治疗有效．

Effect of Clinic Treatment by Tropicamide Esculin-digitalisglycosides Combination Eye Drops on Low Myopia of Children

Objective To investigate the effects of tropicamide and esculin-digitalisglycosides combination eye drops on low myopia of children （age ranging from 6 to 14）. Methods Eighty children with 160 eyes of low myopia in the outpatient department of ophthalmology of our hospital were chose from July 2010 to April 2013, then the patients were equally divided into four groups： the control, esculin-digitalisglycosides eye drops, tropicamide, and tropicamide and eseulin-digitalisglycosides combination groups. The naked vision and myopia correction of each group were compared before and after treatment for two weeks, and the treatment effects were compared among four groups. Results （l） The results showed there were no significant changes before and after treatment in the control, esculin-digitalisglycosides eye drops and tropicamide groups （P〉0.05） ; （2） On the contrast, the tropicamide and esculin-digitalisglycosides combination have significantly improved naked vision and myopia correction after 2 weeks （P 〈 0.05） ; （3） Prior to the treatment, there was no gYoups （P〈0.05） ; （4） After treatment, group under tropicamide and esculin- significant difference among four digitalisglycosides combined wasstatistical different from the other groups treated with other three eye drops （P 〈 0.05） ; However, there was no statistical difference among groups in these three eyedrops. Conclusion Esculin-digitalisglycosides combined with tropicamide was the most effective treatment for low myopia of children.