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An exhausted phenotype of TH2 cells is primed by allergen exposure,but not reinforced by allergen-specific immunotherapy |
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| Authors: | Shu-Hung Wang Ulrich M. Zissler Maren Buettner Sonja Heine Alexander Heldner Sebastian Kotz Lisa Pechtold Josephine Kau Mirjam Plaschke Julia T. Ullmann Ferdinand Guerth Madlen Oelsner Francesca Alessandrini Simon Blank Adam M. Chaker Carsten B. Schmidt-Weber Constanze A. Jakwerth |
| Affiliation: | 1. Center of Allergy & Environment (ZAUM), German Research Center for Environmental Health, Technical University of Munich and Helmholtz Center Munich, Munich, Germany Members of the German Center of Lung Research (DZL), CPC-M, Munich, Germany Member of the Helmholtz I&I Initiative, Munich, Germany;2. Center of Allergy & Environment (ZAUM), German Research Center for Environmental Health, Technical University of Munich and Helmholtz Center Munich, Munich, Germany;3. Institute of Computational Biology, Helmholtz Center Munich, German Research Center for Environmental Health, Neuherberg, Germany;4. Department of Otorhinolaryngology and Head and Neck Surgery, Medical School, Technical University of Munich, Munich, Germany;5. Center of Allergy & Environment (ZAUM), German Research Center for Environmental Health, Technical University of Munich and Helmholtz Center Munich, Munich, Germany Members of the German Center of Lung Research (DZL), CPC-M, Munich, Germany Member of the Helmholtz I&I Initiative, Munich, Germany Department of Otorhinolaryngology and Head and Neck Surgery, Medical School, Technical University of Munich, Munich, Germany |
| Abstract: | |
| Keywords: | AIT CTLA-4 PD-1 proallergic TH2 T-cell exhaustion |