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Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics |
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| Authors: | Nazanin Zounemat Kermani Mansoor Saqi Paul Agapow Stelios Pavlidis Chihhsi Kuo Kai Sen Tan Sharon Mumby Kai Sun Matthew Loza Frederic Baribaud Ana R. Sousa John Riley Asa M. Wheelock Craig E. Wheelock Bertrand De Meulder Jim Schofield Stephany Sánchez-Ovando Jodie Louise Simpson Katherine Joanne Baines Peter A. Wark Charles Auffray Sven-Erik Dahlen Peter J. Sterk Ratko Djukanovic Ian M. Adcock Yi-ke Guo Kian Fan Chung U-BIOPRED Project Team |
| Affiliation: | 1. Department of Computing & Data Science Institute, Imperial College London, London, UK;2. Department of Computing & Data Science Institute, Imperial College London, London, UK National Heart & Lung Institute, Imperial College London, London, UK;3. Department of Otolaryngology, National University of Singapore, Singapore, Singapore;4. National Heart & Lung Institute, Imperial College London, London, UK;5. Janssen Research and Development, High Wycombe, UK;6. Respiratory Therapeutic Unit, GSK, Stockley Park, UK;7. Department of Medicine Solna & Center for Molecular Medicine & Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden;8. European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Lyon, France;9. Faculty of Medicine, Southampton University, Southampton, UK NIHR Southampton Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK;10. Priority Research Centre for Healthy Lungs, Faculty of Health and Medicine, University of Newcastle, Newcastle, NSW, Australia;11. Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands |
| Abstract: | |
| Keywords: | asthma bioinformatics endotypes precision medicine systems biology |