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Drug-specific T-cell responses in patients with liver injury following treatment with the BACE inhibitor atabecestat
Authors:Paul J. Thomson  Laila Kafu  Xiaoli Meng  Jan Snoeys  An De Bondt  Dries De Maeyer  Hans Wils  Laurent Leclercq  Petra Vinken  Dean J. Naisbitt
Affiliation:1. MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK;2. Drug Metabolism and Pharmacokinetics, Janssen R&D, Beerse, Belgium;3. Discovery Sciences, Janssen R&D, Beerse, Belgium;4. Non-Clinical Safety, Janssen R&D, Beerse, Belgium
Abstract:
Keywords:drug-induced liver injury  human  immune system  T-lymphocytes
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