不同日龄新生小鼠视网膜组织学观察

目的 通过对不同日龄新生小鼠视网膜组织学观察，了解小鼠出生后视网膜进一步发育的情况。 方法 对出生后1～20天小鼠的视网膜进行光镜检查，同时对出生后1～3天小鼠视网膜进行放射自显影检查。 结果 新生小鼠(小于3天)视网膜组织只有色素上皮细胞层、神经母细胞层和神经节细胞层，随着日龄的增加，视网膜逐渐发育分化，至20天时视网膜组织才发育完善。 结论 20天前新生小鼠的视网膜是一种发育不完善的组织，可考虑用作移植供体。 (中华眼底病杂志, 1999, 15: 174-176)

A histological observation on the retinas from neonatal mice of different day-ages

Objective To study the progressive development of the retinas through an observation on the histological changes of the retinas from neonatal mice of different day ages. Methods The retinas from the mice of 1 to 20 days of age were examined by light microscopy,and from 1 to 3 days,by autoradiography. Results The retinas of the mice below 3 days of age only had the RPE cells layer,the neuroblast layer and the ganglion cell layer.With the increase in day age,the retinas developed gradually and would be mature in the 20 th day. Conclusions The retinas of mice is a kind of immature tissue before the 20 th days,so it can be considered as transplantation donors.