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复方盐酸特比萘芬搽剂的稳定性研究
引用本文:罗世英,陈华萍.复方盐酸特比萘芬搽剂的稳定性研究[J].中国药业,2005,14(9):39-40.
作者姓名:罗世英  陈华萍
作者单位:1. 广东医学院药理教研室,广东,湛江,524023
2. 广东医学院附属医院药剂科,广东,湛江,524023
基金项目:广东省湛江市科技攻关项目
摘    要:目的:探讨复方盐酸特比萘芬搽剂的稳定性.方法:通过光照试验、加速试验、室温留样试验,以主药含量、溶液外观性状为指标,考察制剂的稳定性.结果:两种主药的含量在加速试验及室温留样试验中变化很小;在光照试验中水杨酸含量稍有下降,但含量均在标示量的90%以上,均在含量限度范围内;外观性状未见变化.结论:复方盐酸特比萘芬搽剂在无强光直射下稳定性好.

关 键 词:盐酸特比萘芬  搽剂  稳定性
文章编号:1006-4931(2005)09-0039-02
收稿时间:2004-11-03
修稿时间:2005-07-04

Research on Stability of Compound Terbinafini Hydrochloridum Liniment
Luo Shiying,Chen Huaping.Research on Stability of Compound Terbinafini Hydrochloridum Liniment[J].China Pharmaceuticals,2005,14(9):39-40.
Authors:Luo Shiying  Chen Huaping
Abstract:Objective:To study the stability of compound terbinafini hydrochloridum limiment.Methods:Using drug contents of two main ingredients,appearance and character as the quality indexes,the stability of compound terbinafini hydrochloridum liniment were investigated by accelerated experiment and room temperature experiment and light influencing- factor test.Results:The results showed that the two main drug contents changed very small except the salicylic acid contents decresed a little in the light influencing- factor test,but the contents of the main drugs were all in the requiral range,more than 90% .The appearance and character did not change.Conclusion:The stability of compound terbinafini hydrochloridum liniment is good without the directly shining of large quantity light.
Keywords:terbinafini hydrochloridum  liniment  stability
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