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Conventional viral cultures and shell vial assay for diagnosis of apparently culture-negativeCoxiella burnetii endocarditis |
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| Authors: | R. Gil-Grande J. M. Aguado C. Pastor M. García-Bravo C. Gómez-Pellico F. Soriano A. R. Noriega |
| Affiliation: | (1) Department of Internal Medicine Unit of Infectious Diseases, Hospital 12 de Octubre, 28041 Madrid, Spain;(2) Department of Clinical Microbiology, Unit of Infectious Diseases, Hospital 12 de Octubre, 28041 Madrid, Spain;(3) Department of Clinical Microbiology, Fundación Jiménez Díaz, 28040 Madrid, Spain |
| Abstract: | A patient with culture-negative endocarditis was diagnosed with Q fever endocarditis based on the results of serological tests and positive leukocyte cultures obtained using conventional viral cultures and the shell vial technique. This case report suggests that isolation ofCoxiella burnetii from blood may allow better diagnostic and therapeutical evaluation of patients with Q fever endocarditis. The use of both conventional and shell vial viral cultures is recommended for the isolation ofCoxiella burnetii from the blood of patients with apparently culture-negative endocarditis. |
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