| 碘化二甲基木防己碱对清醒及急性肾型高血压大鼠的降压作用 |
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| 引用本文： | 刘军保,车锡平. 碘化二甲基木防己碱对清醒及急性肾型高血压大鼠的降压作用[J]. 药学学报, 1984, 19(10): 790-791 |
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| 作者姓名： | 刘军保 车锡平 |
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| 作者单位： | 西安医学院药学系药理学教研室 |
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| 摘 要： | In acute renal hypertensive rats, the blood pressure could be reduced from 148.8±7.9 mmHg to 123.6±9.3 mmHg by intravenous injection of dimethyl trilobine iodide (DTI) at the dosage of 0.5 mg/kg. The hypotensive effect persisted more than 40 minutes.DTI also lowered the blood pressure of unanesthetized rats by feeding 3～10 mg/kg daily for 28 days, but it did not affect the SGPT of rats.
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| 关 键 词： | 碘化二甲基木防己碱 急性肾型高血压大鼠 降压作用 |
| 收稿时间： | 1983-11-14 |
EFFECTS OF DIMETHYL TRILOBINE IODIDE(DTI) ON BLOOD PRESSURE OF UNANESTHETIZED AND ACUTE RENAL HYPERTENSIVE RATS |
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| LIU Jun-Bao and CHE Xi-Ping. EFFECTS OF DIMETHYL TRILOBINE IODIDE(DTI) ON BLOOD PRESSURE OF UNANESTHETIZED AND ACUTE RENAL HYPERTENSIVE RATS[J]. Acta pharmaceutica Sinica, 1984, 19(10): 790-791 |
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| Authors: | LIU Jun-Bao and CHE Xi-Ping |
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| Abstract: | In acute renal hypertensive rats, the blood pressure could be reduced from 148.8±7.9 mmHg to 123.6±9.3 mmHg by intravenous injection of dimethyl trilobine iodide (DTI) at the dosage of 0.5 mg/kg. The hypotensive effect persisted more than 40 minutes.DTI also lowered the blood pressure of unanesthetized rats by feeding 3～10 mg/kg daily for 28 days, but it did not affect the SGPT of rats. |
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| Keywords: | Acute renal hypertensive rats Hypotensive effect Dimethyl trilobine iodide |
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