药物爱维治与胞二磷胆碱治疗脑梗塞患者对比研究

目的 :观察爱维治治疗对急性脑梗塞患者球结膜微循环(BCM )、经颅多普勒超声 (TCD )、内皮素 (ET)、血小板P 选择素CD62 p(CD62 p)及红细胞变形指数 (DI)的影响。方法 :1 1 0例急性脑梗塞患者分为爱维治组 60例、二磷胆碱组 5 0例 ,检测二组患者治疗前后BCM、TCD、ET、CD62 p及DI的变化。结果 :治疗后爱维治组BCM明显改善 ,TCD血流明显增加 ,DI明显增强 ,CD62pET明显降低 ,与胞二磷胆碱组比差异显著 (P <0 .0 1 )。结论 :爱维治治疗可改善微循环、促进脑代谢、减少有害物质的产生及释放 ,对脑梗塞的康复有益。

Compared Study between Drug of Actovegm and Cghidimi Diphosphatis Cholinum on Patients of Cerebral Inferction

Observe the effects of Actovegin treatment on Bulber Conjunctive Microciroulation(BCM),Transcranl Doppler(TCD),Endothelin(ET),P selection CD 62p (CD 62p ) and Deformity Index(DI) in cerebral infarct ion patients.Method: 110 paitents with cerebral infarction were divided into two groups:60 patients in therapy group received by Actovegin,while the rest in control group treated by Cytidini Diphosphatis Cholinum.The changes of BCM,TCD,E T,CD 62p and DI have been observed.Results: After the treatment 15 days above the experimental ind ex were improvement but the Actovegin groups are Better than the cytidimi Diphos phalio cholinum( P< 0.01 ). Conclusion: That Actovegin could refine microcirculation,improve cerebral metabolism,decrease the synthesis and release of toxic substance and s hows a great benefit on the recovery of cerebral infarction.