Cardio-metabolic risk in 5-year-old children prenatally exposed to maternal psychosocial stress: the ABCD study |
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| Authors: | Aimée E van Dijk Manon van Eijsden Karien Stronks Reinoud JBJ Gemke Tanja GM Vrijkotte |
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| Affiliation: | (1) Department of Public Health, Academic Medical Center - University of Amsterdam, Amsterdam, the Netherlands;(2) Department of Epidemiology, Documentation and Health Promotion, Public Health Service of Amsterdam (GGD), Amsterdam, the Netherlands;(3) Department of Paediatrics, VU University Medical Center, Amsterdam, the Netherlands |
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| Abstract: | Background Recent evidence, both animal and human, suggests that modifiable factors during fetal and infant development predispose for cardiovascular disease in adult life and that they may become possible future targets for prevention. One of these factors is maternal psychosocial stress, but so far, few prospective studies have been able to investigate the longer-term effects of stress in detail, i.e. effects in childhood. Therefore, our general aim is to study whether prenatal maternal psychosocial stress is associated with an adverse cardio-metabolic risk profile in the child at age five. |
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