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正交试验优化健脑软脉颗粒乙醇提取工艺研究
引用本文:李建利,陈学忠. 正交试验优化健脑软脉颗粒乙醇提取工艺研究[J]. 内蒙古中医药, 2011, 30(5): 94-95
作者姓名:李建利  陈学忠
作者单位:四川省中医药科学院中医研究所,610031
摘    要:目的:对健脑软脉颗粒乙醇提取工艺进行优化。方法:采用正交试验法,以淫羊藿苷的含量和干浸膏收率为考察指标,对乙醇浓度、提取时间、提取次数和溶剂用量等4个因素进行研究。结果:最佳工艺为用10倍量的70%乙醇回流提取2次,每次1.0h。结论:该工艺提取效率较高,合理、稳定可行,适合工业化生产。

关 键 词:健脑软脉颗粒  正交试验  淫羊藿苷  提取工艺

Orthogonal optimization of the ethanol extraction technology for Jiannao Ruannai Granules
Jian-Li LI,Chen xue zhong. Orthogonal optimization of the ethanol extraction technology for Jiannao Ruannai Granules[J]. Nei Mongol Journal of Traditional Chinese Medicine, 2011, 30(5): 94-95
Authors:Jian-Li LI  Chen xue zhong
Affiliation:(Institute of Tradtional Chinese Medical Sichuan Province Academy of Chinese Medcial Sciences)
Abstract:Objective: To optimize the ethanol extraction technology for Huanghaoxiaoyan Granules. Methods: Orthogonal test was adopted in the study, on the ethanol concentration, extraction time, extraction times and solvent dosage of 4 factors,mad the rate of harvesting of the extract,the contents of ammidin were used as indices of appraisal. Results: The best technology for the use of 8 times 60% ethanol and extracted three times, each time 1.5h. Conclusion: The application of the extraction process is efficient,reasonable and practicable,suitable for industrial production.
Keywords:Jiannao Ruanmai Granules  Orthogonal experiment  annidin  extraet artwork
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