Streptococcal protein G: A sensitive tool for detection of antibodies to human immunodeficiency virus proteins in Western blot analysis |
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| Authors: | L. Björck J. Blomberg |
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| Affiliation: | (1) Department of Medical Microbiology, University of Lund, Sölvegatan 23, 223 62 Lund, Sweden |
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| Abstract: | Protein G is a cell wall protein of group C and G streptococci which binds human IgG antibodies of all four subclasses with high affinity. This property of the molecule was utilized to develop a sensitive Western blot assay to detect antibodies against HIV proteins in patient sera. |
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