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高脂喂养大鼠内脏脂肪组织C反应蛋白的表达
引用本文:代玲俐,李晓永,林宁,董艳,苏青.高脂喂养大鼠内脏脂肪组织C反应蛋白的表达[J].中华内分泌代谢杂志,2008,25(1):323-325.
作者姓名:代玲俐  李晓永  林宁  董艳  苏青
作者单位:上海交通大学医学院附属新华医院内分泌科,200092;
摘    要:The abdominal visceral fat content in obese SD rats induced by high fat diet for 10 weeks was significantly higher than that in control group (26±6 vs 13±3)g,P<0.01] ,along with increased CRP mRNA expression in abdominal visceral fat (0.901±0.085 vs O. 402±0.036, P<0.01). As compared with normal control group, in the high fat group the concentrations of CRP in portal vein (743.8±95.8 vs 558.3 ±118.3) mg/L, P<0.01] and peripheral vein(596.3±38.9 vs 485.8±30.2) mg/L,P<0. 05] were higher. The concentration of CRP in portal vein was significantly higher than that in peripheral vein in high fat diet group(P<0.01) ,but this was not evident in control group. These results suggest that the increased CRP expression in visceral adipose tissue may partially account for the elevation of serum CRP in obesity.

关 键 词:C反应蛋白    肥胖    脂肪组织    高脂饮食    

Expression of C-reactive protein in visceral adipose tissue of rat with high fat diet
DAI Ling-li,LI Xiao-yong,LIN Ning,DONG Yan,SU Qing.Expression of C-reactive protein in visceral adipose tissue of rat with high fat diet[J].Chinese Journal of Endocrinology and Metabolism,2008,25(1):323-325.
Authors:DAI Ling-li  LI Xiao-yong  LIN Ning  DONG Yan  SU Qing
Abstract:
Keywords:C-reactive proteinObesityAdipose tissueHigh-fat diet
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