山西有偿献血地区某村HBV、HCV、HIV感染现状分析

目的了解山西省农村有偿献血地区HBV、HCV、HIV感染状况及有偿献血对其分布的影响.方法对某村的946名20～65岁居民进行调查,采用ELISA法分别检测血清中HBsAg、HBsAb、HBeAg、HBeAb、anti-HCV和HIV抗体.结果HIV抗体全为阴性,HBsAg、HBsAb、HBeAg、HBeAb、anti-HCV的阳性率分别为5.3%、54.5%、2.5%、22.5%、1.7%;其中有偿献血人员108名,相应的阳性率分别为0.9%、63.9%、0.9%、18.5%、4.6%,从未有偿献血人员838名,相应的阳性率分别为5.8%、53.3%、2.7%、23.0%、1.3%.与未有偿献血的研究对象相比,曾经有偿献血的研究对象HBsAg、HBsAb和anti-HCV的阳性率差异有显著性.结论该村未发现HIV感染者,HBV、HCV感染与其他地区无明显不同,有偿献血人员HCV感染率较高.

Prevalence of HBV, HCV and HIV among village residents in a rural area with commercial blood donors in Shanxi province

Objective To determine the prevalence of HBV, HCV and HIV among village residents with commercial blood donors and to explore the impact of paid blood donation on disease infection. Methods The serum of HBsAg, HBsAb, HBeAg, HBeAb, anti-HCV and anti-HIV were analysed by ELISA among 946 voluntary residents aged 20-65 years old in a rural community. Results None was positive for HIV. The positive rates of HBsAg, HBsAb, HBeAg, HBeAb, anti-HCV were 5.3%, 54.5%, 2.5%, 22.5%, and 1. 7% among 946 subjects respectively, 0.9%, 63.9%, 0.9%, 18.5%, 4.6% among 108 paid blood donors respectively, and 5.8%, 53.3%, 2.7%, 23.0%, 1.3 % among remaining 838 subjects without a history of commercial blood donation respectively. The positive rates of HBsAg, HBsAb and anti-HCV were different between the donors and the others. Conclusions Higher prevalence of HBV, HCV and HIV were not different in this rural community among people with a history of paid blood donation compared with other rural areas. But HCV infection seems to be more prevalent among paid blood donors.