Gastric necrosis in newborns: a report of 11 cases |
| |
Authors: | G Pelizzo R Dubois A Lapillonne X Lainé O Claris R Bouvier J P Chappuis |
| |
Institution: | Department of Pediatric Surgery, H?pital E. Herriot, 69003 Lyon, France, FR Neonatal Intensive Care Unit, H?pital E. Herriot, 69003 Lyon, France, FR Department of Pathology, H?pital E. Herriot, 69003 Lyon, France, FR
|
| |
Abstract: | Eleven neonates ranging in gestational age from 34 to 40 weeks presented with gastric necrosis. The 4 full-term neonates
showed sudden-onset hemorrage and “coffee-ground” vomiting; in the 7 premature babies the initial clinical finding was abdominal
distention. The criteria for diagnosis were: perinatal distress in prematures and transient neonatal respiratory distress
in full-term babies. Radiographic evidence of gastric distention was typical and preceded clinical signs of hematemesis and
gastric perforation. Surgery was performed in 8 patients; 3 received medical treatment. At surgery 1␣total and 3 subtotal
gastrectomies and 4 segmental gastric resections were performed. Three of these patients died post-operatively as a consequence
of multiorgan failure; a second look was necessary in one patient 1 week after surgery because of prepyloric perforation due
to ulcers. Biopsy specimens taken from the site of perforation demonstrated extensive necrosis; ulceration was disseminated
in the surrounding gastric mucosa; no signs of phlogosis were detected. The diagnosis, treatment, and physiopathologic considerations
are reviewed.
Accepted: 6 November 1997 |
| |
Keywords: | Gastric infarction Gastric necrosis Spontaneous gastric perforation Neonatal gastric perforation Peptic ulcer disease in children |
本文献已被 SpringerLink 等数据库收录! |
|