| 糖尿病红细胞膜Na^＋—K^＋—ATP酶活性的改变及其影响因素 |
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| 引用本文： | 邓华聪 邱鸿鑫. 糖尿病红细胞膜Na^＋—K^＋—ATP酶活性的改变及其影响因素[J]. 重庆医科大学学报, 1992, 17(3): 193-196 |
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| 作者姓名： | 邓华聪 邱鸿鑫 |
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| 作者单位： | 重庆医科大学第一医院内科内分泌组(邓华聪，邱鸿鑫，汪恕萍，罗荣，沈萍菇)，重庆医科大学第一医院内科内分泌组(粟绍初) |
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| 摘 要： |
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| 关 键 词： | 红细胞膜 糖尿病 酶 |
THE CHANGE OF NA~(+)-K~(+)-ATPase ACTIVITY IN ERYTHROCYTES FROM NIDDM PATIENTS |
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| Deng Huacong. THE CHANGE OF NA~(+)-K~(+)-ATPase ACTIVITY IN ERYTHROCYTES FROM NIDDM PATIENTS[J]. Journal of Chongqing Medical University, 1992, 17(3): 193-196 |
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| Authors: | Deng Huacong |
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| Affiliation: | Deng Huacong,Department of Internal Medicine,The First Hospitanl |
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| Abstract: | Na+-K+-ATPase activity of the erythrocyte plasma membrane in noninsulin-de- pendent diabetes mellitus (NIDDM) was studied together with the red cell deform-ability (RCD) and other influencing factors. Comparing with the normal controls, Na+-K+-ATPase activity, Mg++-ATPase activity, and RCD in diabetics were significantly decreased, and the erythrocyte membrane cholesterol and lipid peroxide, fasting blood glucose, and glycosylated hemoglobin were significantly increased. The change of Na+-K+-ATPase activity was positively correlated with RCD, and inversely correlated with fasting blood glucose, erythrocyte membrane cholesterol, and lipid peroxide. The results suggested that the change of Na+-K+-ATPase activity in erythrocyte may contribute to the alterations of RCD in diabetics |
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| Keywords: | NIDDM Na+-K+-ATPase activity Red cell deformability |
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