| 血清可溶性B7-H4在淋巴瘤患者诊断中的临床意义 |
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| 引用本文： | 谢敏瑚,王亚萍,卢志贤. 血清可溶性B7-H4在淋巴瘤患者诊断中的临床意义[J]. 放射免疫学杂志, 2012, 25(4): 442-443 |
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| 作者姓名： | 谢敏瑚 王亚萍 卢志贤 |
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| 作者单位： | 无锡市第三人民医院检验科,214041 |
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| 摘 要： | 目的：探讨血清可溶性B7-H4（sB7-H4）在淋巴瘤患者检测中的临床意义。方法：用ELISA夹心法检测52例淋巴瘤患者与50例健康者血清sB7-H4水平。结果：霍奇金病、非霍奇金淋巴瘤患者血清sB7-H4水平分别为（45.66±12.48μg/L、50.24±14.52μg/L）明显高于健康者水平（26.47±10.35μg/L）,差异有统计学意义（P〈0.01）。结论：sB7-H4与淋巴瘤的发病有关,对淋巴瘤的辅助诊断具有一定的临床意义。
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| 关 键 词： | 可溶性 B7-H4 霍奇金淋巴瘤 非霍奇金淋巴瘤 |
Clinical Significance of Serum Soluble B7-H4 in Diagnosis of Patients with Lymphoma |
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| Xie Min-hu , Wang Ya-ping , Lu Zhi-xian. Clinical Significance of Serum Soluble B7-H4 in Diagnosis of Patients with Lymphoma[J]. Journal of Radioimmanology, 2012, 25(4): 442-443 |
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| Authors: | Xie Min-hu Wang Ya-ping Lu Zhi-xian |
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| Affiliation: | Department of Clinical Laboratory,Wuxi No.3 Hospital,Wuxi(214041),China |
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| Abstract: | Objective To evaluate the clinical significance of serum soluble B7-H4(sB7-H4) in patients with lymphoma.Methods Enzyme-linked immunosorbent assay was used to detect the level of serum soluble B7-H4 in 52 patients with lymphoma,compared with 50 healthy individuals.Results The level of serum soluble B7-H4 in Hodgkin’s disease group(45.66±12.48μg/L) and non-Hodgkin’s lymphoma(50.24±14.52μg/L) was increased significantly than the control group(26.47±10.35μg/L;all P<0.01).Conclusion sB7-H4 is relevant to morbidity of lymphoma,which possess certain clinical significance in aided diagnosis of lymphoma. |
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| Keywords: | soluble B7-H4 Hodgkin’s lymphoma non-Hodgkin’s lymphoma |
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