| 酒精性肝硬化患者血清内毒素、IL-6、IL-8和PRL检测的临床意义 |
| |
| 引用本文： | 冯飞燕,周卓.酒精性肝硬化患者血清内毒素、IL-6、IL-8和PRL检测的临床意义[J].放射免疫学杂志,2012,25(2):132-133. |
| |
| 作者姓名： | 冯飞燕 周卓 |
| |
| 作者单位： | 1. 浙江省诸暨市中心血站,311800
2. 浙江省诸暨市人民医院,311800 |
| |
| 摘 要： | 目的:探讨了酒精性肝硬化患者血清内毒素、IL-6、IL-8和PRL水平的变化及临床意义。方法:采血鲎试验、放射免疫分析对31例酒精性肝硬化患者进行了血清内毒素、IL-6、IL-8和PRL的检测,并与35名正常人作比较。结果:酒精性肝硬化患者血清内毒素、IL-6、IL-8和PRL水平均非常显著地高于正常人组(P<0.01),且血清内毒素水平与IL-6、IL-8和PRL水平呈正相关(r=0.4788、0.5126.0.6137,P<0.01)。结论:检测酒精性肝硬化患者血清内毒素、IL-6、IL-8和PRL水平的变化,对该病的诊断、治疗和预后观察均有一定的临床实用价值。
|
| 关 键 词： | 酒精性肝硬化 内毒素 白细胞介素-6 白细胞介素-8 垂体泌乳素 |
Clinical Significance of Serum Endotoxin, IL-6, IL-8 and PRL Levels in Patients with Alcoholic Liver Cirrhosis |
| |
| Feng Fei-yan
,
Zhao Zhuo.Clinical Significance of Serum Endotoxin, IL-6, IL-8 and PRL Levels in Patients with Alcoholic Liver Cirrhosis[J].Journal of Radioimmanology,2012,25(2):132-133. |
| |
| Authors: | Feng Fei-yan Zhao Zhuo |
| |
| Institution: | Feng Fei-yan, Zhao Zhuo Zhuji Municipal Central Blood Station, Zhufi( 311800 ), China; A Zhuji Municipal People＇s Hospital, Zhuji( 310800 ), China |
| |
| Abstract: | Objective To explore the clinical significance of serum endotoxin, IL-6, IL-8 and PRL levels in patients with alcoho- lic liver cirrhosis. Methods Serum endotoxin（ with limulus test）, serum IL-6, IL-8, PRL（with RIA）levels were determined in 31 pa- tients with alcoholic liver cirrhosis and 35 normal controls. Results The serum endotoxin, IL-6, IL-8, PRL levels were significantly higher than those in controls （ P 〈 0.01 ）. Serum endotoxin levels were positively correlated with IL-6, IL-8, PRL levels （ r = 0. 4788, 0. 5126,0. 6137 ,P 〈 0.01 ）. Conclusion Detection of serum endotoxin, IL-6, IL-8, PRL levels is clinically useful for diagnosis, treat- ment and predicting prognosis in patients with alcoholic liver cirrhosis. |
| |
| Keywords: | alcoholic liver cirrhosis endotoxin interleukin-6 （ IL-6） interleukin-8 （ IL-8 ） prolactin （ PRL ） |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
