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氟比洛芬酯对胃癌手术患者血清M-CSF和IL-8水平的影响
引用本文:郑闽江,颜凤凤,朱贵芹.氟比洛芬酯对胃癌手术患者血清M-CSF和IL-8水平的影响[J].放射免疫学杂志,2012,25(5):502-503.
作者姓名:郑闽江  颜凤凤  朱贵芹
作者单位:连云港市第一人民医院东方医院麻醉科,222042
摘    要:目的:探讨了氟比洛芬酯对胃癌手术患者血清M-CSF和IL-8水平的影响。方法:60例胃癌手术患者随机分为使用氟比洛芬酯(A组)和不使用氟比洛芬酯(B组),每组30例。在麻醉诱导前、拔管后分别测定患者血清M-CSF和IL-8浓度。结果:拔管后B组水平较A组明显升高(P〈0.05)。结论:氟比洛芬酯可降低胃癌患者血清M-CSF和IL-8水平。

关 键 词:胃癌  氟比洛芬酯  巨噬细胞集落刺激因子  白细胞介素-8

Effect of Flurbiprofen Axetil on Serum M-CSF, IL-8 Levels in Patients Undergoing Gastric Cancer Surgery
Zheng Min-jiang , Yan Feng-feng , Zhu Gui-qin.Effect of Flurbiprofen Axetil on Serum M-CSF, IL-8 Levels in Patients Undergoing Gastric Cancer Surgery[J].Journal of Radioimmanology,2012,25(5):502-503.
Authors:Zheng Min-jiang  Yan Feng-feng  Zhu Gui-qin
Institution:Department of Anesthesiology,Lianyungang First People’s Hospital East Hospital,Lianyungang(222042),China
Abstract:Objective To explore the effect of fiurbiprofen axetil on serum M-CSF and IL-8 levels in the patients undergoing gastric cancer surgery.Methods 60 patients were randomized divided into 2 group with 30 cases each.The patients in group A were given flubiprofen axetil and those in group B were not as the controls.Serum M-CSF,IL-8(with RIA)levels were measured before anesthesia and after extubation.Results The levels of serum M-CSF,IL-8 were significantly higher in group B than those in group A(P<0.05) Conclusion Flubiprofen axetil could reduce serum M-CSF,IL-8 levels in patients undergoing gastric cancer surgery.
Keywords:gastric cancer  flurbiprofen axetil  macrophage stimulating factor(M-CSF)  interleukin-8(IL-8)
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