|
|||||
|
|
| 桑白皮等中药提取物对胰岛素促进离体肝脏葡萄糖消耗的影响 | |
| 引用本文： | 汪宁,朱荃,周义维,童黄锦. 桑白皮等中药提取物对胰岛素促进离体肝脏葡萄糖消耗的影响[J]. 时珍国医国药, 2006, 17(4): 513-514 |
| 作者姓名： | 汪宁 朱荃 周义维 童黄锦 |
| 作者单位： | 1. 南京中医药大学国家规范化中药药理实验室,江苏,南京,210029;安徽中医学院药学院,安徽,合肥,230038 2. 南京中医药大学国家规范化中药药理实验室,江苏,南京,210029 3. 安徽中医学院药学院,安徽,合肥,230038 |
| 基金项目： | 安徽省高等学校青年教师科研资助计划立项项目(No.2005jq1099) |
| 摘 要： | 目的利用大鼠离体肝脏灌流技术评价中药提取物在胰岛素存在时对离体肝组织消耗葡萄糖的影响。方法采用离体肝灌流技术,将中药提取物加入灌流液中,观察灌流液中谷丙转氨酶(ALT)及葡萄糖浓度的变化,用以评价中药提取物在胰岛素存在时对离体肝脏消耗葡萄糖的影响与肝脏损伤状况。结果受试的中药提取液在120 m in内对灌流液中谷丙转氨酶没有显著性影响,桑白皮、桑枝、桑寄生提取物能显著降低灌流液中葡萄糖的浓度。结论桑白皮、桑寄生、桑枝提取物在胰岛素存在时能增加离体肝脏葡萄糖的消耗。 |
| 关 键 词： | 离体肝脏灌流 桑寄生 桑白皮 桑枝 葡萄糖消耗 谷丙转氨酶 |
| 文章编号： | 1008-0805（2006）04-0513-02 |
| 收稿时间： | 2005-12-22 |
| 修稿时间： | 2006-02-16 |
The Effects of Extracts of Several Chinese Medicines on Glucose Consumption Stimulated by Insulin of Rat Isolated Liver |
|
| WANG Ning,ZHU Quan,ZHOU Yi-wei,TONG Huang-jing. The Effects of Extracts of Several Chinese Medicines on Glucose Consumption Stimulated by Insulin of Rat Isolated Liver[J]. Lishizhen Medicine and Materia Medica Research, 2006, 17(4): 513-514 | |
| Authors: | WANG Ning ZHU Quan ZHOU Yi-wei TONG Huang-jing |
| Affiliation: | 1. China National Standard Laboratory of Pharmacology for Chinese Materia Medicine of Nanjing University of TCM ,Nanjing 210029, China ; 2. Department of Pharmacy, Anhui College of TCM ,Hefei 230038, China |
| Abstract: | ObjectiveEvaluate the effects of several Chinese medicines on glucose consumption of isolated liver in the presence of insulin.MethodsThe technology of rat isolated liver perfusion was used for observing the changes of ALT and glucose concentration in perfused medium so as to assay glucose consumption and liver damage.ResultsThere was no significant changes of ALT in perfused medium during the 120 minutes,perfusion in all tested experimental groups,extracts of Cortex Mori,Herba taxilli and Ramulus Mori significantly decreased glucose concentration in perfused medium.ConclusionCortex Mori,Herba taxilli and Ramulus Mori could increased glucose consumption of rat isolated liver in the presence of insulin. |
| Keywords: | Isolated liver perfusion Ramulus Mori Cortex Mori Herba taxilli Glucose consumption ALT |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |