| 经皮二尖瓣球囊成形术前后RAAS的变化 |
| |
| 引用本文： | 周胜华,沈向前,祁述善,林振武. 经皮二尖瓣球囊成形术前后RAAS的变化[J]. 中南大学学报(医学版), 1994, 0(5) |
| |
| 作者姓名： | 周胜华 沈向前 祁述善 林振武 |
| |
| 作者单位： | Department of Internal Medicine，The Second Affiliated Hospital，Hunan Medical University |
| |
| 摘 要： | 对１７例风湿性心脏病二尖瓣狭窄患者经皮二尖瓣球囊成形术术前和术后一周分别检测血浆肾素（ＰＲＡ）、血管紧张素Ⅱ（ＡＴ－Ⅱ）和醛固酮（ＡＬＤ）。结果表明：术前ＰＲＡ，ＡＴ－Ⅱ和ＡＬＤ明显高于对照组；术后血流动力学明显改善，并伴有ＡＴ－Ⅱ和ＡＬＤ水平显著降低（Ｐ＜０．０５）。ＡＴ－Ⅱ下降与左房压下降呈弱正相关（ｒ＝０．４３ｌ）。揭示在心功能不全早期已有肾素－血管紧张素－醛固酮系统（ＲＡＡＳ）过度激活；术后，在血流动力学改善的同时，ＲＡＡＳ也有相应改变。
|
| 关 键 词： | 二尖瓣狭窄；球囊扩充；肾素－血管紧张素系统；血液动力学 |
THE ALTERED LEVELS OF PLASMA RENIN-ANGIOTENSIN-ALDOSTERONE BEFORE AND AFTER PERCUTANEOUS BALLOON MITRAL VALVULOPLASTY |
| |
| Zhou Shenghua, Shen Xiangqian, Qi Shushan. THE ALTERED LEVELS OF PLASMA RENIN-ANGIOTENSIN-ALDOSTERONE BEFORE AND AFTER PERCUTANEOUS BALLOON MITRAL VALVULOPLASTY[J]. Journal of Central South University. Medical sciences, 1994, 0(5) |
| |
| Authors: | Zhou Shenghua Shen Xiangqian Qi Shushan |
| |
| Abstract: | he levels of plasma renin(PRA),angiotensin-2(AT-2)and aldosterone(ALD)in 20healthy subjects and 17 patients with rheumatic mitral stenosis were maesured by RIA beforeand after percutaneous balloon mitral valvuloplasty(PBMV),and the hemodynamic changeswere recorde during PBMV. The results showed that AT-2 and ALD were significantly lowerafter PBMV and PRA was little higher but without significance(P>0.05).The decreasedAT-2 positively correlated with the change of the left atrial pressure(r=0.431).We con-clude that PBMV may correct the superactive renin-angiotensin-aldosterone system(RAAS)and partially improve hemodynamics of the patients with rheumatic mitral stenosis. |
| |
| Keywords: | mitral valve stenosis balloon dilatation renin-angiotensin system hemodynamics |
| 本文献已被 CNKI 等数据库收录！ |
