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Treatment strategies in rhinoconjunctivitis and asthma during pregnancy
Authors:Prieto Lastra L  Pérez Pimiento A  González Sánchez L A  Rodríguez Cabreros M I  Rodríguez Mosquera M  García Cubero J A
Institution:1. Allergy Department, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain;2. Pharmacy Department, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain;1. Skin and Allergy Hospital, Helsinki University Central Hospital, Helsinki, Finland;2. Department of Medical Genetics, University of Helsinki, Helsinki, Finland;3. The Finnish Institute for Health and Welfare, Helsinki, Finland;4. Department of Pulmonary Diseases and Clinical Allergology, Turku University Hospital and University of Turku, Finland;1. Institute of Public Health, National Yang-Ming University, Taiwan;2. Center of Neuropsychiatric Research, National Health Research Institutes, Taiwan;3. Department of Epidemiology and Biostatics, Michigan State University, USA;4. Department of Addiction Science, Taipei City Psychiatric Centre, Taipei City Hospital, Taiwan;5. Center for Drug Abuse and Addiction, China Medical University and Graduate Institute of Clinical Medicine, China Medical University, Taiwan;1. Graduate Institute of Biotechnology, National Chung-Hsing University, Taichung 402, Taiwan;2. Taiwan Coral Research Center, National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan;3. Institute of Marine Biotechnology, National Dong-Hwa University, Pingtung 944, Taiwan;1. Department of Pathology, Peking University People’s Hospital, Xicheng District Xizhimen South Street No. 11, Beijing, 100044, China;2. Department of Hematology, Peking University People’s Hospital, Xicheng District Xizhimen South Street No. 11, Beijing, 100044, China;3. Department of Pathology, Xinjiang Medical University Cancer Hospital, New City District Suzhou Street No. 789, Urumqi, 830000, China
Abstract:BackgroundThe incidence of asthma is high, especially in young people, a population group that in-cludes women of reproductive age. We reviewed recent publications on asthma control during pregnancy to avoid undesired effects on both the mother and fetus. The prevalence of rhinoconjunctivitis is also high, although this disease is often under-treated by physicians. The use of β2-agonists, corticoids (systemic/inhaled/nebulized), epinephrine and specific allergen immunotherapy is discussed.MethodsWe reviewed recent publications on asthma during pregnancy as well as other articles of interest. Articles providing data on drug therapy, overall strategies and patient education were selected. Sufficient drugs are available for the management of this disease and under-treatment cannot be justifiedConclusionsPregnancy is not a disease, but constitutesa period when special care must be taken with underlying diseases. The aim of asthma treatment during pregnancy is to prevent fetal complications due to the effects of medication and asthma crises by keeping the mother symptom free and preventing possible exacerbations. Almost all authors agree that asthma crises in pregnant women should be treated no differently from those in non-pregnant women. Treatment of rhinoconjunctivitis should not be stopped during pregnancy since a wide variety of FDA category B drugs is available. Specific allergen immunotherapy should not be suspended during pregnancy as it is not contraindicated. However, this therapy should not be initiated during pregnancy.
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