钩端螺旋体病26例临床分析

目的总结钩端螺旋体病的流行病学特征和临床特点，探讨其防治对策。方法对1996年1月．2006年6月住院的26例钩端螺旋体病患者临床资料进行分析。结果钩端螺旋体病主要以青壮年为主，患者大多数为农民，以7-10月份为发病率高峰；有少数病例临床表现不典型；本组26例中误诊12例（46．15％），其与首诊误诊、大剂量使用青霉素和未早期用激素有关。结论临床医师要结合流行病学特征和临床特点进行综合分析，掌握钩体病各型及其后发症的诊断与鉴别诊断。提高基层医务人员对钩体病的认识，掌握有效的救治方法仍是目前基层医院所面临的问题。

Clinical analysis of 26 leptospirosis patients

Objective To summarize the epidemiologic features and clinical characters of leptospirosis,and discuss the corresponding strategy of prevention and treatment.Methods The clinical material of 26 inpatients with leptospirosis treated from Jan.1996 to Jun.2006 were retrospectively analyzed.Results The majority of these patients were young adults and peasants.The peak of incidence rate occurred from Jul.to Oct.12 cases(46.15%)were misdiagnosed;the misdiagnosis was associated with the factors including initial misdiagnosis,administration of high dose penicillin and not use hormone in the early stage.Conclusion The clinicians need to make a comprehensive analysis of both epidemiologic and clinical features of leptospirosis for correct diagnosis and treatment of the disease.