TACE联合PSE在原发性肝癌并脾亢治疗中的应用

目的:探讨原发性肝癌行TACE联合不同程度PSE对术后血常规及肝功能部分化验指标的影响。方法:2014年4月至2014年6月对本院原发性肝癌伴脾功能亢进行TACE联合PSE治疗的患者45例，按照脾栓塞比例分为:脾栓塞程度＜50%(A组)、50%-60%(B组)，术前及术后每周复查外周血WBC、PLT、AST、ALT、TBI至术后第8周，并进行Child分级。结果:A、B两组患者术后外周血中WBC、PLT计数均较术前有所升高，B组升高更明显，在随访末期A组明显呈下降趋势；A、B两组术前术后肝功能无明显变化。结论:在TACE联合PSE治疗中，脾栓塞比例是影响外周血WBC、PLT的重要因素；不同脾栓塞比例对肝功能无明显影响，高比例脾栓塞可加重栓塞后反应。

Application of TACE combined with PSE in the treatment of primary liver cancer and hypersplenism

Objective:To investigate the effect of primary liver cancer treat by transcatheter arterial chemoembolization(TACE) combined with partial splenic embolization(PSE).Methods:All 45 case of primary liver cancer patients with splenic function treat by TACE combined with PSE were divided in to splenic embolization degree<50% (group A),50%-60%(group B),preoperative and postoperative weekly review peripheral WBC,PLT,AST,ALT,TBI to 8 weeks after surgery.Results:A,B two groups postoperative WBC and PLT count in peripheral blood was increased,compared with preoperative group B increased more obviously.A,B two groups of preoperative postoperative liver function has no obvious change.Conclusion:Proportion of splenic embolization is one of the important factors affecting peripheral WBC,PLT.Different splenic embolization percentage had no obvious effect on liver function,high proportion of splenic embolization can increase reaction after embolization.