ADAPT技术治疗急性大血管闭塞性卒中

目的 探讨使用直接抽吸首次通过技术(a direct aspiration first-pass technique,ADAPT)治疗急性大血管闭塞性卒中的安全性和有效性.方法 回顾性分析12例采用ADAPT技术治疗急性大血管闭塞性卒中病人的临床资料.应用脑梗死溶栓(thrombolysis in cerebral i...

A direct aspiration first-pass technique for the treatment of acute large vessel occlusion stroke

Objective To investigate the safety and efficacy of a direct aspiration first-pass technique(ADAPT)in the treatment of acute large vessel occlusion stroke.Methods Clinical data of 12 patients with acute large vessel occlusion stroke undergoing ADAPT were analyzed retrospectively.Thrombolysis in cerebral infarction(TICI)was used to assess the recanalization of occluded vessels,and the National Institute of Health Stroke Scale(NIHSS)score was used to assess the neurological deficit.The patients were followed up for 90 days after the operation,and the independent living conditions were evaluated by modified Rankin scale(mRS).Results ADAPT was performed 2.0±1.8 times in average in this study.The mean time between onset and femoral artery puncture was 360.8±170.9 min,and the mean time between femoral artery puncture and vascular recanalization was 133.1±43.2 min.Eleven patients were achieved effective recanalization(TICI grade 2b to grade 3)immediately after operation,including TICI grade 3 in 7 patients,grade 2b in 4 and grade 2a in 1.There was significant difference in NIHSS score before and after the operation(P<0.05).Two patients died.Ten patients were followed up for 90 days,mRS score showed 1 point in 5 patients,3 points in 2,4 in 1 and 5 in 2.Conclusion ADAPT is safe and effective for acute large vascular occlusive stroke.