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Conversion factors for determining organ doses received by paediatric patients in high-resolution single slice computed tomography with narrow collimation
Authors:Michael C Seidenbusch  Dietrich Harder  Dieter F Regulla  Karl Schneider
Institution:1. Paediatric Radiology, Institute for Clinical Radiology, Dr. von Hauner''s Children''s Hospital, Ludwig-Maximilians-University Munich, Lindwurmstr. 4, 80337 Munich, Germany;2. Medical Physics and Biophysics, Georg-August-University Göttingen, Konrad-Adenauer-Str. 26, 37075 Göttingen, Germany;3. Research Unit Medical Radiation Physics and Diagnostics, Helmholtz Zentrum München - German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany;1. IRMA/LCPR-AC/CE, UMR 6249 CNRS, Université de Franche-Comté, BP 71427, 25211 Montbéliard, France;2. Centre Hospitalier Belfort Montbéliard, Service d''Oncologie et de Radiothérapie, site du Mittan, 56 boulevard du Maréchal Juin, 25209 Montbéliard, France;1. Department of Biochemistry and Molecular & Cellular Biology, Georgetown University, Washington DC, USA;2. Pediatrics, Division of Developmental Nutrition, University of Arkansas for Medical Sciences, Little Rock, AR, USA;3. Mass Spectrometry Data Center, National Institute of Standards and Technology (NIST), Gaithersburg MD, USA;4. Columbia University, New York, NY, USA;5. Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, USA;6. Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah 22254, Saudi Arabia;1. Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ankara University, Ankara, Turkey;2. Department of Endodontics, Faculty of Dentistry, Ankara University, Ankara, Turkey
Abstract:Estimations of organ doses DT received during computed tomographic examinations are usually performed by applying conversion factors to basic dose indicators like the computed tomography dose index (CTDI) or the dose-length-product (DLP). In addition to the existing conversion factors for beam apertures of 5 mm or 10 mm, we present new DLP-DT conversion factors adapted to high-resolution CT (HRCT) examinations of infants and young children with beam apertures of the order of 1 mm and under consideration of bow tie filtration. Calculations are performed on mathematical MIRD phantoms for an age range from 0, 1, 5, 10, 15 up to (for comparison) 30 years by adapting PCXMC, a Monte Carlo algorithm originally developed by STUK (Helsinki, Finland) for dose reconstructions in projection radiography. For this purpose, each single slice CT examination is approximated by a series of corresponding virtual planar radiographies comprising all focus positions. The transformation of CT exposure parameters into exposure parameters of the series of corresponding planar radiographies is performed by a specially developed algorithm called XCT. The DLP values are evaluated using the EGSRay code. The new method is verified at a beam aperture of 10 mm by comparison with formerly published conversion factors. We show that the higher spatial resolution leads to an enhanced DLP-DT conversion factor if a small organ (e. g. thyroid gland, mammae, uterus, ovaries, testes) is exactly met by the chosen CT slice, while the conversion factor is drastically reduced if the chosen CT slice is positioned above or below the organ. This effect is utilized for dose-saving examinations with only a few single slices instead a full scan, which technique is applied in about 10% of all paediatric chest CT examinations.
Keywords:High-resolution CT  organ doses  dose length product  CTDI  computed tomographic dose index  conversion factors  fan beam filter  HRCT  Organdosen  Dosis-Längen-Produkt  CTDI  Konversionsfaktoren  Fächerstrahlfilter
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