多发性脑梗塞痴呆患者部分抗氧化指标检测及临床意义

检测配对设计的５４例多发性脑梗塞痴呆患者的５４例健康老年人血浆维生素Ｃ、血浆维生素Ｅ含量及血浆和红细胞超氧化物歧化酶活性、血浆和红细胞过氧化脂质、Ｅ－ＳＯＤ值均显著降低（Ｐ＜０．００１），平均Ｐ－ＬＰＯ和Ｅ－ＬＰＯ含量均显著升高；５４例患者的Ｐ－ＶＣ、Ｐ－ＶＥ含量均与Ｐ－ＳＯＤ、Ｅ－ＳＯＤ值呈直线正相关，均与Ｐ－ＬＰＯ、Ｅ－ＬＰＯ含量呈直线负相关；患者病程与Ｐ０ＶＣ、Ｐ－ＶＥ、Ｅ－ＳＯＤ值呈直线负

Measurement of Partial Antioxidation Indices in Multiple Cerebral Infarction Dementia Patients and Its Clinical Significance

The results of measuring plasma vitamin C (P-VC), plasma vitamin E (P-VE) contents , plasma superoxide dismutase activity(P-SODA), erythrocyte superoxide dismutase activity(E-SODA). plasma lipoperoxides(P-LPO) and erythrocyte lipoperoxides (E-LPO) contents of 54 multiple cerebral infarction dementia patients and 54 health aged subjects showed that the average P-VC , P-VE , P-SODA, E-SODA values of the patient group were all significantly lower than those of the control group (P<0. 001). The average P-LPO,E-LPO values of the patient group were all significantly higher than those of the control group (P<0. 001 ).P-VC and P-VE, P-VC and P-SODA, E-SODA, P-VE and P-SODA, E-SODA were all presented positive linear correlation ship. P-VC and P-LPO , E-LPO , P-VE and P-LPO, E-LPO were all in negative linear correlation. The clinical courses of the patient and P-VE, P-VE, E-SODA were all in negative linear correlatioin, but the course and P-LPO, E-LPO were all in positive linear correlation. The degee of intelligence damage and P-VC, P-VE were in all negative lineas correlation. but degree of intelligence damage and PLPO, E-LPO were all in positive linear correlation.