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Resistance to macrolides in Group A streptococci from the European section of Turkey: genetic and phenotypic characterization
Authors:Akata Filiz  Oztürk Devrim  Tansel Ozlem  Tatman-Otkun Müserref  Otkun Metin  Fitoussi Frederic  Bingen Edouard  Tugrul Murat
Affiliation:

a Department of Clinical Bacteriology and Infectious Diseases, Medical Faculty of Trakya University, 22030, Edirne, Turkey

b Service de Microbiologie, Hôpital Robert Debré, 75019, Paris, France

Abstract:The aim of this study was to determine the susceptibilities to macrolides of Group A streptococcal isolates from the European section of Turkey. In the case of resistant isolates, the patterns and genetic mechanisms of erythromycin resistance were studied. Seven (2.7%) of the 260 isolates were resistant to erythromycin. Four of them showed the M phenotype and harboured mefA genes whereas three isolates showed the inducible macrolide, lincosamide and streptogramin B resistance phenotype and harboured ermTR genes. In the European section of Turkey, the current resistance rate of Group A streptococci to macrolides remains low.
Keywords:Group A streptococci   Macrolide resistance   Resistance phenotype   mefA   ermTR
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