| 年轻卵巢恶性肿瘤患者保留生育功能手术总结 |
| |
| 引用本文： | 侯敏敏,郄明蓉,曹泽毅. 年轻卵巢恶性肿瘤患者保留生育功能手术总结[J]. 中德临床肿瘤学杂志, 2006, 5(6): 446-450. DOI: 10.1007/s10330-006-0516-8 |
| |
| 作者姓名： | 侯敏敏 郄明蓉 曹泽毅 |
| |
| 作者单位： | Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu 610041, China |
| |
| 摘 要： | Objection： To evaluate the impact of fertility-preserving surgery and adjuvant chemotherapy on survival and fertility of young patients with ovarian malignant tumors. Methods： Retrospective analysis of 39 patients with ovarian malignant germ cell tumors, 23 patients with malignant epithelial tumors and 4 patients with sexual cord mesenchymal tumors receiving conservative treatments. Results： Two patients lost follow-up （we do not statistics them）. Fifty-nine among 64 patients were alive up to now （92.19%）. The overall survival rate for ovarian epithelial malignancies, malignant germ cell tumors and sexual cord mesenchymal tumors were 95.45%, 89.47% and 100% respectively. Fifteen patients received second operation and recurrence was found in 6 patients. Among the 59 surviving patients, 53 patients have normal menstruation. Thirteen patients among 20 patients who want to pregnant have 15 pregnancies and 9 successful deliveries. Conclusion： The management of fertility-preserving surgery on patients with ovarian malignant germ cell tumors, whatever the FIGO staging is, is a safe option. For patients with ovarian epithelial carcinomas, fertility-preserving surgery only confined to low-stage （stage Ⅰ）, low-grade （G1）, and patients who want keep fertility function seriously. Cisplatinum-based combination chemotherapy is necessary. Standardized chemotherapy has no affection on fertility function.
|
| 关 键 词： | 恶性卵巢瘤 年轻患者 评估效应 间叶细胞 |
| 收稿时间： | 2006-08-09 |
| 修稿时间： | 2006-10-13 |
Evaluation the effect of fertility-preserving surgery on young patients with malignant ovarian tumors |
| |
| Minmin Hou,Mingrong Xi,Zeyi Cao,Ziaoyu Niu,Zhilan Peng,Hongjing Wang,Ai Zheng. Evaluation the effect of fertility-preserving surgery on young patients with malignant ovarian tumors[J]. The Chinese-German Journal of Clinical Oncology, 2006, 5(6): 446-450. DOI: 10.1007/s10330-006-0516-8 |
| |
| Authors: | Minmin Hou Mingrong Xi Zeyi Cao Ziaoyu Niu Zhilan Peng Hongjing Wang Ai Zheng |
| |
| Affiliation: | (1) Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, 610041, China |
| |
| Abstract: | Objection:To evaluate the impact of fertility-preserving surgery and adjuvant chemotherapy on survival and fertility of young patients with ovarian malignant tumors.Methods:Retrospective analysis of 39 patients with ovarian malignant germ cell tumors,23 patients with malignant epithelial tumors and 4 patients with sexual cord mesenchymal tumors receiving conser-vative treatments.Results:Two patients lost follow-up(we do not statistics them).Fifty-nine among 64 patients were alive up to now(92.19%).The overall survival rate for ovarian epithelial malignancies,malignant germ cell tumors and sexual cord mes-enchymal tumors were 95.45%,89.47% and 100% respectively.Fifteen patients received second operation and recurrence was found in 6 patients.Among the 59 surviving patients,53 patients have normal menstruation.Thirteen patients among 20 patients who want to pregnant have 15 pregnancies and 9 successful deliveries.Conclusion:The management of fertility-preserving surgery on patients with ovarian malignant germ cell tumors,whatever the FIGO staging is,is a safe option.For patients with ovarian epithelial carcinomas,fertility-preserving surgery only confined to low-stage(stage I),low-grade(G1),and patients who want keep fertility function seriously.Cisplatinum-based combination chemotherapy is necessary.Standardized chemotherapy has no affection on fertility function. |
| |
| Keywords: | ovarian malignant tumor fertility-preserving young patients ovarian function |
| 本文献已被 CNKI 维普 万方数据 SpringerLink 等数据库收录！ |
|
