痫病中医证素分布规律

目的:分析痫病的中医证素分布规律。方法:检索中国期刊全文数据库、中国生物医学文献数据库、万方医学和维普资讯等数据库,收集、整理2009-2019年间有关痫病辨证分型的文献,采用SPSS 24.0统计学软件建立数据库,对痫病中医证型、证素分布规律进行频次分析。结果:规范后提取痫病证名共29个,主要证型依次为风痰闭阻证(19.28%)、痰火扰神证(16.87%)、脾虚痰湿证(10.04%)、瘀阻脑络证(8.84%)等。提取证素20个,其中病性证素13个,病位证素7个。病性证素以痰(30.72%)、闭(12.78%)、动风(11.75%)、气虚(10.31%)和热(火)(9.90%)为主,病位证素中以肝(27.34%)、心神(脑)(20.97%)和脾(19.85%)为主。在证素组合中,以三证素组合最常见,累计频率为41.22%,其中两病性证素+单一病位证素组合最常见,频率为34.69%。两病性组合时,痰+热(火)、痰+气虚和气虚+血虚出现的频率较高,频率分别为30.43%、18.12%和13.77%。结论:痫病涉及病理因素复杂,主要为痰,常与热(火)、气虚、血瘀、动风和闭相互为病,病位在肝。

Distribution Rules of TCM Syndrome Elements in Epilepsy

Objective:To analyze the distribution rules of TCM syndrome elements in epilepsy.Methods:Through the retrieval of Chinese Journal Full-text Database(CNKI),Chinese biomedical literature database,Wanfang medicine and VIP information database,the literature on syndrome differentiation and classification of epilepsy between 2009 and 2019 was collected and sorted out.SPSS 24.0 statistical software was used to establish the database to analyze the frequency of TCM syndrome type and syndrome element distribution of epilepsy.Results:After the standardization,a total of 29 epileptic syndrome names were extracted.The main syndrome types were wind phlegm blocking syndrome(19.28%),phlegm fire disturbing mind syndrome(16.87%),spleen deficiency phlegm dampness syndrome(10.04%),blood stasis blocking brain collaterals syndrome(8.84%).A total of 20 syndrome elements were extracted,including 13 disease nature syndrome elements and 7 disease location syndrome elements.Phlegm(30.72%),blockage(12.78%),moving wind(11.75%),qi deficiency(10.31%)and heat(fire)(9.90%)were the main disease nature syndrome elements.Liver(27.34%),mind(brain)(20.97%)and spleen(19.85%)were the main disease location syndrome elements.In terms of syndrome element combination,three syndrome element combination is the most common,the cumulative frequency is 41.22%,among which two disease nature syndrome elements plus single disease location syndrome element combination is the most common,and the frequency is 34.69%.When two disease natures are combined,the frequency of phlegm+heat(fire),phlegm+qi deficiency and qi deficiency+blood deficiency were 30.43%,18.12%and 13.77%respectively.Conclusion:Epilepsy involves complex pathological factors,mainly phlegm,often with heat(fire),qi deficiency,blood stasis,intermingled wind and blockage for mutual disease causes,and the disease location is in the liver.