| 关于黄芪、丹参注射液抗四氯化碳致小鼠肝损伤作用的商榷 |
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| 引用本文： | 王玉凤,邵胜男,袁静,黄学武.关于黄芪、丹参注射液抗四氯化碳致小鼠肝损伤作用的商榷[J].时珍国医国药,2010,21(2). |
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| 作者姓名： | 王玉凤 邵胜男 袁静 黄学武 |
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| 作者单位： | 1. 安徽中医学院中医临床学院,安徽,合肥,230038
2. 合肥工业大学化工学院,安徽,合肥,230009 |
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| 摘 要： | 目的 研究黄芪、丹参注射液及复方芪参注射液抗CCl_4致小鼠肝损伤作用.方法 采用四氯化碳诱导小鼠急性肝损伤模型,从整体水平上观察复方芪参注射液抗CCl_4致小鼠肝损伤作用.结果 复方芪参注射液及阳性药组(市售丹参注射液、黄芪注射液及两者配伍)对CCl_4致小鼠急性肝损伤无显著保护作用.结论 黄芪、丹参注射液对CCl_4致小鼠急性肝损伤的保护作用,值得商榷.
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| 关 键 词： | 丹参 黄芪 急性肝损伤 |
Discussion about the Protective Effect of Huangqi and Danshen Injection on CCl_4-induced Liver Injury in Mice |
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| WANG Yu-feng,SHAO Shen-nan,YUAN Jing,HUANG Xue-wu.Discussion about the Protective Effect of Huangqi and Danshen Injection on CCl_4-induced Liver Injury in Mice[J].Lishizhen Medicine and Materia Medica Research,2010,21(2). |
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| Authors: | WANG Yu-feng SHAO Shen-nan YUAN Jing HUANG Xue-wu |
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| Institution: | WANG Yu-feng1,SHAO Sheng-nan2,YUAN Jing1,HUANG Xue-wu1 (1.Anhui College of Traditional Chinese Medicine,Hefei 230038,China,2.Hefei University of Technology,Hefei 230009,China) |
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| Abstract: | Objective To investigate the protective effect of compound Huangqi and Danshen injection on CCl4-induced liver injury in mice.Methods Overall observation on the protective effect of compound Huangqi and Danshen injection on liver injury was made by establishing CCl4-induced acute liver injury model in mice.Results Compound Huangqi and Danshen injection and positive control group had no significant protective effect against CCl4-induced acute liver injury.Conclusion It is still questionable to use Huangqi an... |
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| Keywords: | Astragalus membranaceus Salvia miltiorrhiza Acute liver injury |
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