细辛脑注射液与地塞米松磷酸钠配伍稳定性研究 |
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引用本文: | 董文文,李锦燊,李明艳. 细辛脑注射液与地塞米松磷酸钠配伍稳定性研究[J]. 黑龙江医药, 2010, 23(5): 721-722 |
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作者姓名: | 董文文 李锦燊 李明艳 |
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作者单位: | 广西医科大第四附属医院,广西,柳州,545005;广西医科大第四附属医院,广西,柳州,545005;广西医科大第四附属医院,广西,柳州,545005 |
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摘 要: | 目的:考察细辛脑注射液与地塞米松磷酸钠注射液在50g.L-1葡萄糖中的稳定性。方法:观察配伍液的外观、测定不溶性微粒、pH值,采用HPLC法测定细辛脑的含量。结果:配伍液在室温时4h内无明显外观、pH值的变化,含量在90%以上,不溶性微粒符合规定。结论:细辛脑与地塞米松磷酸钠注射液配伍室温4h内基本稳定。
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关 键 词: | 细辛脑 地塞米松磷酸钠 稳定性 高效液相色谱法 |
Effect on the Stability of Asarone Injection with Dexamethasone Sodium Phosphate Injection |
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Affiliation: | Dong Wenwen,et al The No. Affiliated Hospital of Guangxi Medical University(Guangxi Liuzhou 545005) |
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Abstract: | Objective:To study the stability of Asarone injection with Dexamethasone Sodium Phosphate injection in 50g·L-1 glucose injection.Methods:The changes in appearance and pH value of the mixture within 4 hours at room temperature were observed and the content of Asarone was determined by HPLC.Results:No significant changes were noted in appearance,pH and content of the mixture within 4 hours.Conclusion:The Dexamethasone Sodium Phosphate had no effect on the stability of Asarone within 4 hours at room temperature. |
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Keywords: | Asarone Dexamethasone Sodium Phosphate Stability HPLC |
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