| 尿NAG、尿微量白蛋白检测在泌尿系结石早期肾损害监测中的临床意义 |
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| 引用本文： | 王露萍,梁卓寅,梁志雄,李逊. 尿NAG、尿微量白蛋白检测在泌尿系结石早期肾损害监测中的临床意义[J]. 现代泌尿外科杂志, 2005, 10(3): 134-135 |
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| 作者姓名： | 王露萍 梁卓寅 梁志雄 李逊 |
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| 作者单位： | 广州医学院第一附属医院微创外科中心,广东广州,510230 |
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| 摘 要： | 目的探讨尿N-乙酰β-D氨基葡萄糖苷酶(NAG)、尿微量白蛋白(mA1b)在泌尿系结石患者早期肾功能损害监测中的临床意义。方法自2000年10月至2003年6月对167例肾结石患者及97例对照病例,分别采用对硝基苯底物的比色法和免疫比浊法测定尿NAG和mAlb水平,根据患者尿Cr水平,计算尿NAG/Cr、mAlb/Cr比值,并对两组间NAG/Cr、mAlb/Cr比值进行比较分析。结果肾结石患者尿NAG/Cr、mAlb/Cr分别为1.41U/mol及21.8mg/mol,明显高于对照组(P<0.01)。结论尿NAG、mAlb检测是反映早期肾功能损害的敏感指标之一,可作为监测肾结石患者早期肾功能变化的指标。
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| 关 键 词： | 肾结石 N-乙酰β-D氨基葡萄糖苷酶 微量白蛋白 |
| 文章编号： | 1009-8291(2005)03-0134-02 |
| 修稿时间： | 2004-09-14 |
Clinical significance of urinary N-acetyl-beta-D-glucosaminidase(NAG) and mAlb as early markers of renal function damage in patients with renal calculi |
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| Wang Luping,Liang Zhuoyin,Liang Zhixiong,Li Xun. Clinical significance of urinary N-acetyl-beta-D-glucosaminidase(NAG) and mAlb as early markers of renal function damage in patients with renal calculi[J]. Journal of MOdern Urology, 2005, 10(3): 134-135 |
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| Authors: | Wang Luping Liang Zhuoyin Liang Zhixiong Li Xun |
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| Abstract: | Objective To evaluate the clinical significance of urinary mAlb and NAG in the detection of renal function damage in patients with renal calculi. Methods 167 patients with renal calculi and 97 control cases were examined during October 2000 to June 2003. Immunoturbidimetry and enzyme appearance were used to detect urinary NAG and mAlb. The NAG/Cr and mAlb/Cr of the two groups were analysed. Results The level of NAG/Cr and mAlb/Cr in patients with renal calculi was significantly higher than that in the control group (P<0.01). Conclusion The detection of urinary mAlb and NAG may be useful and sensitive in monitoring renal function damage in patients with renal calculi. |
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| Keywords: | renal calculi N-acetyl-beta-D-glucosaminidase(NAG) microalbumin |
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