| 双氢睾酮体外培养人毛囊中差异表达的miR-133b对人毛乳头细胞的增殖及诱导能力的影响 |
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| 引用本文： | 邓文佳,邓长健,韩乐,刘本,唐鑫,万苗坚.双氢睾酮体外培养人毛囊中差异表达的miR-133b对人毛乳头细胞的增殖及诱导能力的影响[J].中山大学学报(医学科学版),2021,42(2):202-208. |
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| 作者姓名： | 邓文佳 邓长健 韩乐 刘本 唐鑫 万苗坚 |
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| 作者单位： | 1.中山大学附属第三医院皮肤性病科，广东 广州 510630;2.龙岗区人民医院耳鼻咽喉科，广东 深圳 518172 |
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| 基金项目： | 国家自然科学基金(81872542) |
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| 摘 要： | 目的探究不同浓度双氢睾酮（DHT）对毛囊生长和毛囊细胞增殖的影响及其与miR-133b表达的关系，然后进一步探究miR-133b对毛乳头细胞的增殖和诱导能力的影响。
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| 关 键 词： | miR-133b 双氢睾酮 毛囊 毛乳头细胞 |
| 收稿时间： | 2019-11-03 |
Differential Expression of miR-133b in Human Hair Follicles Treated with DHT in Vitro and Its Functional Analysis in Human Dermal Papille Cells |
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| Wen-jia DENG,Chang-jian DENG,Le HAN,Ben LIU,Xin TANG,Miao-jian WAN.Differential Expression of miR-133b in Human Hair Follicles Treated with DHT in Vitro and Its Functional Analysis in Human Dermal Papille Cells[J].Journal of Sun Yatsen University(Medical Sciences),2021,42(2):202-208. |
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| Authors: | Wen-jia DENG Chang-jian DENG Le HAN Ben LIU Xin TANG Miao-jian WAN |
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| Institution: | 1.Department of Dermatology and Venereology，The Third Affiliated Hospital of Sun Yat-sen University，Guangzhou 510630，China;2.Department of Otorhinolaryngology，the People's Hospital of Longgang District，Shenzhen 518172，China |
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| Abstract: | ObjectiveTo explore the effects of different concentrations of 5α-dihydrotestosterone （DHT） on growth and proliferation of human hair follicles （HFs） and their relationship with miR-133b expression， then further explore the role of miR-133b in the proliferation and inducibility of human dermal papille cells. |
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| Keywords: | miR-133b 5α-dihydrotestosterone hair follicles dermal papille cells |
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