痴呆危险因素人群归因分值的城乡差异

目的 使用人群归因分值(population attributable fractions,PAF)探讨痴呆危险因素所造成痴呆患者的比例,为今后痴呆的早期预防和干预提供建议.方法 采用随机整群抽样的方法选取3 361名≥65岁的老年人进行调查,使用x2检验分析危险因素的城乡差异.在主成分分析探索危险因素之间重叠效应的基...

Urban-rural differences in population attributable fractions for risk dementia factors

  Objective  Based on the population attributable fraction (PAF), the ratio of dementia induced by risk factors was estimated to provide early prevention and intervention strategies.  Methods  To assess the urban-rural differences of risk factors of dementia using Chi-square test in 3 361 persons which are selected using random cluster sampling and 65 years or older. Based on the results from principal components analysis, we calculated the weighted PAF of each risk factor contributing to dementia.  Results  The overall weighted PAF for dementia risk factors in urban was 39.51%, and the weighted PAF for individual risk factors was hypertension (10.46%), overweight and obesity (9.78%), smoking (5.69%), low education (5.55%), diabetes (3.93%), lack of physical exercise (2.75%) and lack of social interaction (1.35%). The overall weighted PAF for dementia risk factors in rural was 31.66%, and the weighted PAF for individual risk factors was low education (9.21%), hypertension (6.60%), overweight and obesity (4.96%), lack of social interaction (4.94%), smoking (4.44%), diabetes (1.51%).  Conclusions  There was a significant difference in weighted PAF of each risk factor between urban and rural areas. And prevention and early intervention strategies for dementia should be given different emphasis in urban and rural areas.