| 低强度脉冲式超声波机械力生物链内源性干细胞激活与功能修复的研究进展 |
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| 引用本文： | 夏术阶,管延杰. 低强度脉冲式超声波机械力生物链内源性干细胞激活与功能修复的研究进展[J]. 山东大学学报(医学版), 2021, 59(9): 37-42. DOI: 10.6040/j.issn.1671-7554.0.2021.0966 |
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| 作者姓名： | 夏术阶 管延杰 |
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| 作者单位： | 上海交通大学附属第一人民医院泌尿外科,上海200080 |
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| 基金项目： | 国家自然科学基金(81930018) |
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| 摘 要： | 近年来,以低强度脉冲式超声波(LIPUS)为代表的机械力治疗手段已被广泛用于康复医学、骨折修复、神经损伤修复、泌尿系统疾病等领域.目前研究表明,LIPUS可能通过激活内源性干细胞参与组织修复,但是机械力如何通过生物链的转化而激活干细胞的具体机制尚不明确,因此对机械力生物链传导过程的进一步探索有助于揭示LIPUS的作用机...
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| 关 键 词： | 低强度脉冲式超声波 机械力生物链 内源性干细胞 |
Progress on the activation of endogenous stem cells and functional repair in LIPUS mechanotransduction |
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| XIA Shujie,GUAN Yanjie. Progress on the activation of endogenous stem cells and functional repair in LIPUS mechanotransduction[J]. Journal of Shandong University:Health Sciences, 2021, 59(9): 37-42. DOI: 10.6040/j.issn.1671-7554.0.2021.0966 |
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| Authors: | XIA Shujie GUAN Yanjie |
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| Affiliation: | Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China |
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| Abstract: | In recent years, mechanical therapies represented by low-intensity pulsed ultrasound(LIPUS)have been widely used in rehabilitation medicine, fracture repair, nerve injury repair, urinary system diseases and other fields. Current studies have shown that LIPUS may participate in tissue repair by activating endogenous stem cells, but the specific mechanism by which mechanical force activates stem cells through the transformation of the biological chain is still unclear. Therefore, further exploration of the conduction process of mechanotransduction will help to reveal the mechanism of LIPUS and provide reference for subsequent researches and clinical applications. |
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| Keywords: | Low-intensity pulsed ultrasound Mechanotransduction Endogenous stem cells |
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