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椎-基底动脉系统短暂性脑缺血发作患者认知功能的研究
引用本文:韩静,李华,苏俊红. 椎-基底动脉系统短暂性脑缺血发作患者认知功能的研究[J]. 农垦医学, 2006, 28(6): 407-408
作者姓名:韩静  李华  苏俊红
作者单位:石河子大学医学院护理系,832002;石河子大学医学院第三附属医院神经内科,新疆石河子,832000
摘    要:目的:研究椎-基底动脉系统短暂性脑缺血发作(TIA)患者的事件相关电位(P300)变化,探讨其对认知功能的损害以及可能的机制.方法:对30例椎-基底动脉系统TIA患者和30例正常对照组进行简易智能状态检查(MMSE)和听觉p300测试.结果:病例组P300潜伏期较正常对照组延长,波幅较正常对照组降低;2.病例组MMSE总分低于对照组,主要表现在即刻记忆和注意计算两个分项上的得分低于对照组.结论;椎-基底动脉系统TIA患者存在认知功能损害.

关 键 词:椎-基底动脉系统  短暂性脑缺血发作  认知功能  P300

A Study of Cognitive Function in Patients with Transient Ischemic Attack of Vertibrobasilar System
Han Jing,Li Hua,Su Junhong. A Study of Cognitive Function in Patients with Transient Ischemic Attack of Vertibrobasilar System[J]. Agricultural Reclamation Medicine, 2006, 28(6): 407-408
Authors:Han Jing  Li Hua  Su Junhong
Abstract:Objective: To investigate the changes of event related potentials(ERP) on patients with transient ischemic attack(TIA) of Vertibrobasilar System in order to explore the cognitive damages and possible mechanism.Methods:thirty patients with TIA and thirty healthy people as controls were taken mini mental state examination(MMSE)and test P300 through the standard oddball paradigm.Results: The latencies of P300 were prolonged significantly in TIA group compared with normal group.The amplitude of P300 were higher significantly in TIA group compared with normal group;the total marks of MMSE were lower significantly in TIA group,especially in subentry of instanter memory and attention and calculation.Conclusion:The cognitive function of patients with TIA of Vertibrobasilar System were damaged.
Keywords:P300
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