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Pill-induced esophageal injury
Authors:James Walter Kikendall MD  Arnold C. Friedman MD  Morakinyo Anthony Oyewole MD  David Fleischer MD  Col. Lawrence F. Johnson MD
Affiliation:1. Gastroenterology and Radiology Divisions, Walter Reed Army Medical Center, OSC Box 317, Washington, D.C.
2. the Uniformed Services University of the Health Sciences, 20012, Washington, D.C.
3. the Gastroenterology/Hepatology Section, Veterans Administration Medical Center, Washington, D.C.
Abstract:We report four cases of esophageal injury associated with the ingestion of commonly prescribed tablets or capsules. History and clinical characteristics of these cases suggest that the medications failed to transit the esophagus and acted locally to produce esophagitis. A search of English- and foreign-language medical journals documented 221 similar cases due to 26 different types of medication. While most of these esophageal injuries are self-limited and produce no morbidity beyond transient retrosternal pain, odynophagia, and dysphagia, major complications have occurred, such as mediastinal penetration, hemorrhage, and death. Patients should be counseled to take pills in an upright posture with liberal amounts of fluid well before retiring for the night.
Keywords:
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