| 脑组织伊文思兰含量和细胞内游离钙离子浓度与冷冻伤性脑水肿的关系 |
| |
| 引用本文： | 陈立华,曹美鸿,杨于嘉,陶永光,袁贤瑞,何正文. 脑组织伊文思兰含量和细胞内游离钙离子浓度与冷冻伤性脑水肿的关系[J]. 中南大学学报(医学版), 1999, 0(4) |
| |
| 作者姓名： | 陈立华 曹美鸿 杨于嘉 陶永光 袁贤瑞 何正文 |
| |
| 作者单位： | Department of Neurosurgery，Xiangya Hospital，Hunan Medical University，Changsha 410008 |
| |
| 摘 要： | 在大鼠冷冻伤性脑水肿时，观察脑组织伊文思蓝（ Ｅ Ｂ） 含量和突触体内游离钙离子浓度（［ Ｃａ２ ＋ ］ｉ）变化，及其与脑组织水份含量变化之间的关系。结果表明：脑组织水份含量变化与伊文思蓝含量和［ Ｃａ２ ＋ ］ｉ 变化之间，均呈高度正相关。冷冻伤性脑水肿具有细胞毒性脑水肿和血管源性脑水肿特性，即冷冻伤性脑水肿是一种混合性脑水肿。
|
| 关 键 词： | 脑损伤 冷冻伤 脑水肿 细胞内游离钙离子 伊文思蓝 大鼠 |
Relationship between brain edema induced by freezing injury and concentration of Evan blues and cytosolic free calcium in brain tissues |
| |
| Abstract: | The authors studied the changes of Evan blues(EB) of brain tissues and concentration of cytosolic free calcium ([Ca 2+ ]i), and relationship between them and water content of brain tissues following freezing brain edema in rats, to elucidate mechanism and type of brain edema induced by freezing injury. The results indicated that there were close positive relationship between water content and EB of brain tissues, and between [Ca 2+ ]i and water content. We found that not only cytotoxic brain edema(intracellular edema) occurred but also occurred vasogenic brain edema(extracellular edema) followed by blood brain barrier breakdown after brain edema. Freezing brain edema is mixed brain edema. |
| |
| Keywords: | brain injury freezing brain edema Evans blue cytosolic free calcium * rat |
| 本文献已被 CNKI 等数据库收录！ |
