Cystic angiomatosis of bone with sclerotic changes mimicking osteoblastic metastases |
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Authors: | Tsuyoshi Ishida MD Howard D Dorfman MD German C Steiner MD Alex Norman MD |
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Institution: | (1) Section of Orthopaedic Pathology, Department of Orthopaedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210th Street, Bronx, 10467-2490 New York, New York, USA;(2) Department of Pathology and Laboratory Medicine, Hospital for Joint Diseases Orthopaedic Institute, 111 East 210th Street, Bronx, 10467-2490 New York, New York, USA;(3) Department of Radiology, New York Medical College, 111 East 210th Street, Bronx, 10467-2490 Valhalla, New York, USA |
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Abstract: | Five unusual cases of cystic angiomatosis of bone which presented with the radiologic appearance of osteoblastic lesions are
reported. Three patients were female (ages 37, 41, and 65 years) and two were male (ages 24 and 66 years). Although cystic
angiomatosis of bone usually produces widespread osteolytic lesions with a honeycombed appearance in the skeletal system,
multiple osteoblastic lesions mimicking metastatic osteoblastic carcinoma are sometimes seen. This radiological presentation
has not been well emphasized in previous reports. Histologically, in addition to the angiomatous lesions, both mature thickened
lamellar bone trabeculae and immature trabeculae of woven bone were found. In one of our patients, increasing density of the
osteoblastic lesions was noted over time. One previous study has suggested that the age of the lesions of cystic angiomatosis
is related to radiographic density. It is important to recognize this uncommon variant of cystic angiomatosis and to include
this entity among the radiologic differential diagnoses when multiple osteoblastic lesions are encountered. |
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Keywords: | Cystic angiomatosis Hemangiomatosis Lymphangiomatosis Osteosclerosis Bone |
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