| 老年心脑血管病及糖尿病患者血浆脂质过氧化物与抗氧化酶测定 |
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| 引用本文： | 黄仲驹,吴长珠,刘友尧,翁元真.老年心脑血管病及糖尿病患者血浆脂质过氧化物与抗氧化酶测定[J].福建医科大学学报,1994(2). |
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| 作者姓名： | 黄仲驹 吴长珠 刘友尧 翁元真 |
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| 作者单位： | 福建医学院医疗系内科教研室，福建医学院生物化学教研室，福建省立医院第二内科 |
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| 摘 要： | 检测老年心脑血管病及糖尿病患者１３３例的血浆脂质过氧化物（ＬＰＯ）、全血超氧化物歧化酶（ＳＯＤ）和谷胱甘肽过氧化物酶（ＧＳＨ－ＰＸ）。冠心病、心肌梗塞的ＬＰＯ比对照组明显上升（Ｐ＜０．０１）；冠心病、心肌梗塞及脑梗塞的ＳＯＤ比对照组及糖尿病组明显降低（Ｐ＜０．０１）；冠心病及脑梗塞ＧＳＨ－ＰＸ比对照组明显降低（Ｐ＜０．０１）；ＧＳＨ－ＰＸ／ＬＰＯ在冠心病、心肌梗塞、脑梗塞和糖尿病都比对照组明显降低（均为Ｐ＜０．０５）。
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| 关 键 词： | 老年人，心、脑血管病，糖尿病，脂质过氧化物，抗氧化酶 |
Determination of Serum LPO and Anti-oxidase of Elder Patients with Cerebrovascular Diseases or Diabetes Mellitus |
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| Huang Zhongju,Wu Changzhu,Liu Youyao,et al.Determination of Serum LPO and Anti-oxidase of Elder Patients with Cerebrovascular Diseases or Diabetes Mellitus[J].Journal of Fujian Medical University,1994(2). |
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| Authors: | Huang Zhongju Wu Changzhu Liu Youyao |
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| Abstract: | This paper investigated and analysed LPO,SOD and GSH-PX in the blood from 133 cases for elderly patients with cerebrovascular diseases and diabetes mellitus.The results show that the contents of LPO for coronary heart diseases and myocardial infarction were increased more remarkably than that of control group(P<0.01).The contents of SOD for coronary heart diseases,myocardial infarction and cerebral infarction GSH-PX for coronary and cerebral infarction,and the rates of GSH-PX/LPO for coronary heart diseases,myocardial infarction,cerebral infarction and diabetes mellitus respectively were decreased more signifiantly than that of control group and diabetes mellitus(P<0.01),and that of control groups(P<0.01and P<0.05).There were no notable difference among all experimental groups.This study reveals that the action of LPO is strong,the system of anti-oxidase is damaged and the response of organism is decreased for elderly patients with above four diseases. |
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| Keywords: | elderly cerebrovascular diseases diabetes mellitus LPO anti-oxidase system |
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