| 西宁地区充血性心衰患者血浆一氧化氮的变化及临床意义 |
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| 引用本文： | 孙斌,尚玲,郗爱旗,褚以德. 西宁地区充血性心衰患者血浆一氧化氮的变化及临床意义[J]. 高原医学杂志, 2007, 17(3): 35-37 |
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| 作者姓名： | 孙斌 尚玲 郗爱旗 褚以德 |
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| 作者单位： | 青海省人民医院ICU科,810007;青海省人民医院老年医学研究所,810007 |
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| 基金项目： | 青海省科技厅自然科学基金项目(编号2006-N-149)部分研究内容 |
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| 摘 要： | 目的:分析西宁地区充血性心力衰竭(CHF)一氧化氮(NO)的含量变化及其临床意义。方法:检测59例临床确诊为CHF的患者血浆NO含量,另选31例健康体检者作为正常对照组。结果:西宁地区CHF患者血浆NO水平明显高于对照组(P<0.01),且心衰程度越重,NO水平越高。结论:血浆NO可作为反映CHF严重程度的客观指标之一,且在CHF病理生理改变中起重要作用。
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| 关 键 词： | 充血性心力衰竭 一氧化氮 西宁地区 |
The Change and Its Significance of Plasma Level of Nitric Oxide in Patients with Congestive Heart Failure in Moderate Altitude Area |
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| Sun Bin,Shang Ling,Xi Aiqi,Chu Yide. The Change and Its Significance of Plasma Level of Nitric Oxide in Patients with Congestive Heart Failure in Moderate Altitude Area[J]. Journal of High Altitude Medicine, 2007, 17(3): 35-37 |
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| Authors: | Sun Bin Shang Ling Xi Aiqi Chu Yide |
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| Abstract: | Objective:To investigate the change and the clinical significance of plasma nitric Oxide (NO) in patients with congestive heart failure(CHF) in moderate area. Methods:Plasma level of NO was measured in 59 patients with CHF and 41 healthy subjects served as normal controls. Results: The plasma level of NO was significantly higher in patients with CHF than in controls (P<0.01) and in which the level of plasma NO was significantly higher in NYHA functional class II~IV. Conclusions:The plasma level of NO can be used as a degree parameter of CHF; NO plays an important rote in pathophysiology of CHF. |
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| Keywords: | Congestive heart failure Nitric oxide High altitude |
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