Permeability of protective gloves to sodium lauryl sulfate. Release chambers used as an in vitro test system |
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Authors: | Dorte W. Ramsing Ann Fullerton |
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Affiliation: | Department of Dermatology, Gentofte Hospital, University of Copenhagen, Denmark;Department of Dermatological Research, Leo Pharmaceutical Products, Denmark |
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Abstract: | Background/aims: Gloves are important and necessary in many occupations especially in wet work. They may offer a protection against harmful materials, but many substances may also penetrate protective gloves. Methods: The permeability of 6 different commonly used protective gloves to the anionic detergent sodium lauryl sulfate (SLS) was investigated. The gloves were tested as membranes in diffusion cells at 32°C. (35S)SLS 1% was used as permeant and synthetic sweat was used as recipient. Samples were counted on a scintillation counter. Results: During a test period of 24 h, none of the gloves tested were found to be permeable to SLS. Conclusions: The gloves tested were found to offer protection against SLS. The difussion cells were useful for in vitro testing of protective gloves under controlled experimental conditions. |
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Keywords: | protective gloves permeation wet work irritants natrium lauryl sulfate diffusion cell |
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