谷氨酸能系统障碍与卒中后抑郁 |
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引用本文: | 高琪,张志珺. 谷氨酸能系统障碍与卒中后抑郁[J]. 中华脑血管病杂志(电子版), 2013, 7(1): 404-408 |
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作者姓名: | 高琪 张志珺 |
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作者单位: | 高琪 (汕头大学医学院第一附属医院神经内科,515041);张志珺 (汕头大学医学院第一附属医院神经内科,515041); |
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摘 要: | 近年来,大量研究表明谷氨酸能系统障碍可能与卒中后抑郁(PSD)的发病机制密切相关。本文主要从外周血小板功能障碍、海马神经元再生及重塑障碍两方面阐述谷氨酸能系统障碍在PSD病理生理机制中发挥的作用。
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关 键 词: | 卒中 抑郁 谷氨酸 |
The dysfunction of glutamatergic system and post-stroke depression |
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Affiliation: | GAO Qi. (Medical School of Southeast University;Department of Neurology, Zhongda Hospital, Southeast University, Nanjing 210009, China) |
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Abstract: | In recent years ,a number of studies indicate that the dysfunction of glutamatergic system may be closely associated with the pathogenesis of post-stroke depression (PSD) .This paper describes the roles of glutamatergic system played in the pathophysiological mechanism of PSD mainly from two aspects as follows : the altered peripheral platelet functions and the dysfunction of neuronal regeneration and remodelling in the hippocampus. |
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Keywords: | Glutamate Post-stroke Depression Platelet |
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