| 谷氨酸能系统障碍与卒中后抑郁 |
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| 引用本文： | 高琪,张志珺.谷氨酸能系统障碍与卒中后抑郁[J].中华脑血管病杂志(电子版),2013,7(1):404-408. |
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| 作者姓名： | 高琪 张志珺 |
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| 作者单位： | 高琪 (汕头大学医学院第一附属医院神经内科,515041)；张志珺 (汕头大学医学院第一附属医院神经内科,515041)； |
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| 摘 要： | 近年来，大量研究表明谷氨酸能系统障碍可能与卒中后抑郁（PSD）的发病机制密切相关。本文主要从外周血小板功能障碍、海马神经元再生及重塑障碍两方面阐述谷氨酸能系统障碍在PSD病理生理机制中发挥的作用。
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| 关 键 词： | 卒中 抑郁 谷氨酸 |
The dysfunction of glutamatergic system and post-stroke depression |
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| Institution: | GAO Qi. (Medical School of Southeast University;Department of Neurology, Zhongda Hospital, Southeast University, Nanjing 210009, China) |
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| Abstract: | In recent years ,a number of studies indicate that the dysfunction of glutamatergic system may be closely associated with the pathogenesis of post-stroke depression （PSD） .This paper describes the roles of glutamatergic system played in the pathophysiological mechanism of PSD mainly from two aspects as follows ： the altered peripheral platelet functions and the dysfunction of neuronal regeneration and remodelling in the hippocampus. |
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| Keywords: | Glutamate Post-stroke Depression Platelet |
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