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Arterial spin labeling: Clinical applications |
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| Authors: | Mai-Lan Ho |
| Affiliation: | Division of Neuroradiology, Mayo Clinic, 200 First St. SW, 55905 Rochester, MN, United States |
| Abstract: | Arterial spin labeling (ASL) is a magnetic resonance imaging perfusion technique that enables quantification of cerebral blood flow (CBF) without the use of intravenous gadolinium contrast. An understanding of the technical basis of ASL and physiologic variations in perfusion are important for recognizing normal variants and artifacts. Pathologic variations in perfusion can be seen in a number of disorders including acute and chronic ischemia, vasculopathy, vascular malformations, tumors, trauma, infection/inflammation, epilepsy and dementia. |
| Keywords: | Arterial spin labeling Cerebral blood flow Perfusion Postlabel delay ACA anterior cerebral artery AVF arteriovenous fistula AVM arteriovenous malformation ASL arterial spin labeling ATA arterial transit artifact ATT arterial transit time CBF cerebral blood flow CBV cerebral blood volume CT computed tomography DCE dynamic contrast-enhanced DSC dynamic susceptibility contrast DVA developmental venous anomaly DWI diffusion-weighted imaging FLAIR fluid-attenuated inversion recovery GRE gradient-recalled echo ICA internal carotid artery IV intravenous MCA middle cerebral artery MR magnetic resonance MRA magnetic resonance angiography ms milliseconds PCA posterior cerebral artery PET positron emission tomography PLD postlabel delay RF radiofrequency SNR signal-to-noise SWI susceptibility-weighted imaging TBI traumatic brain injury |
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