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Treat-and-Extend versus Monthly Regimen in Neovascular Age-Related Macular Degeneration: Results with Ranibizumab from the TREND Study |
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| Authors: | Rufino Silva András Berta Michael Larsen Wayne Macfadden Chrystel Feller Jordi Monés |
| Affiliation: | 1. Department of Ophthalmology, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal;2. Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra (IBILI-FMUC), Portugal;3. Association for Innovation and Biomedical Research on Light and Image (AIBILI), Coimbra, Portugal;4. Department of Ophthalmology, Faculty of Medicine, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary;5. Department of Ophthalmology, Rigshospitalet and Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark;6. Novartis Pharma AG, Basel, Switzerland;7. Institut de la Macula, Barcelona, Spain; Barcelona Macula Foundation, Barcelona, Spain |
| Abstract: | |
| Keywords: | AE adverse event AMD age-related macular degeneration ANCOVA analysis of covariance BCVA best-corrected visual acuity CNV choroidal neovascularization CSFT central subfield thickness ETDRS Early Treatment Diabetic Retinopathy Study IOP intraocular pressure LS least squares nAMD neovascular age-related macular degeneration PRN pro re nata SAE serious adverse event SD standard deviation T&E treat and extend TREND TReat and extEND VA visual acuity VEGF vascular endothelial growth factor |
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