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2型糖尿病肾病患者血浆D-二聚体和纤维蛋白原检测的临床应用
引用本文:徐凤玲,吕江峰.2型糖尿病肾病患者血浆D-二聚体和纤维蛋白原检测的临床应用[J].医学检验与临床,2012,23(2):44-45.
作者姓名:徐凤玲  吕江峰
作者单位:山东省莱芜市人民医院检验科,山东莱芜,271100
摘    要:目的探讨检测血浆D-二聚体(DD)、纤维蛋白原(FIB)水平对2型糖尿痛肾病的临床应用价值。方法对已确诊的184例2型糖尿病患者,其中2型糖尿病肾病患者108例,2型糖尿病患者76例,另选65例健康体检者作为对照组,分别测定各组血浆DDFIB的水平。结果DD、FIB的检测水平在糖尿病各组与对照组之间比较差异有统计学意义(P〈0.01、P〈0.05)。结论2型糖尿病肾病患者检测血浆DD和FIB水平有早期诊断意义。

关 键 词:糖尿病肾病  D-二聚体  纤维蛋白原

The clinical application of plasma D - dimer and fibrinogen detection in patients with type2 diabetic nephropathy
Xu Fengling , Lv Jiangfeng.The clinical application of plasma D - dimer and fibrinogen detection in patients with type2 diabetic nephropathy[J].Medical Laboratory Science and Clinics,2012,23(2):44-45.
Authors:Xu Fengling  Lv Jiangfeng
Institution:(Department of Laboratory Medicine, The People's Hospital of Laiwu City, Laiwu 271100 China)
Abstract:Objective To study the clinical application value of plasma D- dimer(DD) and fibrinogen(FIB) levels in diabetic nephropathy(DN). Methods The levels of DD and FIB from 184 patients with type 2 diabetes meUitus(DM) were detected.These patients were classified into DN group(n = 108) and DM group(n = 76). Other 65 healthy persons were employed as control. Results There was significant difference of DD and fibrinogen levels in all groups as compared with control group(P 〈 0.01 or P 〈 0.05). Conclusion The simultaneous determination of DD and FIB is significant in the early diagnosis of the DN.
Keywords:Diabetic nephropathy  D - dimer  Fibrinogen
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