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Prevalence of acute cardiac disorders in patients with suspected ST-segment elevation myocardial infarction and non-significant coronary artery disease
Authors:H. Andersson  T.E. Christensen  K.A. Ahtarovski  L.E. Bang  P. Hasbak  N. Vejlstrup  F. Pedersen  L. Holmvang  P. Grande  P. Clemmensen  G.S. Wagner
Affiliation:1. Department of Cardiology, The Heart Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark;2. Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark;3. Department of Clinical Physiology, Nuclear Medicine and PET, Diagnostic Centre, Copenhagen University Hospital, Copenhagen, Denmark;4. Department of Medicine, division of Cardiology, Duke University Medical, Center, Durham, NC, USA
Abstract:

Background and purpose

We aimed to study the prevalence of acute cardiac disorders in patients with suspected ST-segment elevation myocardial infarction (STEMI) and non-significant coronary artery disease (CAD).

Methods

From January to October 2012 we consecutively included patients admitted with suspected STEMI and non-significant CAD (coronary artery stenosis diameter < 50%). Patients were diagnosed with acute cardiac disorder in the presence of elevated cardiac biomarkers (troponin T > 50 ng/l or creatine kinase MB > 4 μg/l) or dynamic ECG changes (ST-segment changes or T-wave inversion).

Results

Of the 871 patients admitted with suspected STEMI, 11% (n = 95) had non-significant CAD. Of these, 67% (n = 64) had elevated cardiac biomarkers or dynamic ECG changes and were accordingly diagnosed with acute cardiac disorders. In the remaining 33% (n = 31) of patients, cardiac biomarkers were normal and ECG changes remained stationary.

Conclusions

Acute cardiac disorders were diagnosed in two thirds of patients with suspected STEMI and non-significant CAD.
Keywords:Acute cardiac disorders   ST-segment elevation myocardial infarction   Non-significant coronary artery disease
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